5-Bromo-2-methoxybenzaldehyde → N-(5-Bromo-2-methoxybenzyl)-3-(8-chloro-3-phenylcinnolin-4-yl)aniline

HRID 643320Notes

Reaction equation

HRID 643320 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[N:9][C:8]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[C:7]2[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1.[Br:25][C:26]1[CH:27]=[CH:28][C:29]([O:34][CH3:35])=[C:30]([CH:33]=1)[CH:31]=O>>[Br:25][C:26]1[CH:27]=[CH:28][C:29]([O:34][CH3:35])=[C:30]([CH:33]=1)[CH2:31][NH:24][C:20]1[CH:21]=[CH:22][CH:23]=[C:18]([C:7]2[C:6]3[C:11](=[C:2]([Cl:1])[CH:3]=[CH:4][CH:5]=3)[N:10]=[N:9][C:8]=2[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:19]=1

Participants

3

Reactant 2

HCID 906845-Bromo-2-methoxybenzaldehydeHCID 118566993-(8-Chloro-3-phenyl-cinnolin-4-yl)-phenylamine

Product 1

HCID 11855349N-(5-Bromo-2-methoxybenzyl)-3-(8-chloro-3-phenylcinnolin-4-yl)aniline

Procedure

The title compound was prepared from 3-(8-chloro-3-phenyl-cinnolin-4-yl)-phenylamine and 5-bromo-2-methoxybenzaldehyde according to the procedure of Step 5 Example 6. MS (ES) m/z 529.9.

Sources & evidence

ORD record
ord-e5d48e18c95044a4b0ba2cbf77cd2f0f
Source dataset
uspto-grants-2010_04
Patent number
US07700595B2

Reaction notes

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