3-Methylbenzo(b)thiophene-2-carboxaldehyde → [3-(8-Chloro-3-phenylcinnolin-4-yl)phenyl][(3-methyl-1-benzothien-2-yl)methyl]amine

HRID 643327Notes

Reaction equation

HRID 643327 reaction equation
[CH2:1]([C:8]1[N:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[Cl:25])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4]C=1.[CH3:26][C:27]1[C:28]2[CH:37]=[CH:36][CH:35]=[CH:34][C:29]=2[S:30][C:31]=1[CH:32]=O>>[Cl:25][C:12]1[CH:13]=[CH:14][CH:15]=[C:16]2[C:11]=1[N:10]=[N:9][C:8]([C:1]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:2]=1)=[C:17]2[C:18]1[CH:19]=[C:20]([NH:24][CH2:32][C:31]2[S:30][C:29]3[CH:34]=[CH:35][CH:36]=[CH:37][C:28]=3[C:27]=2[CH3:26])[CH:21]=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 5199183-Methylbenzo(b)thiophene-2-carboxaldehydeHCID 11855621[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl]amine

Product 1

HCID 11854829[3-(8-Chloro-3-phenylcinnolin-4-yl)phenyl][(3-methyl-1-benzothien-2-yl)methyl]amine

Procedure

The title compound was prepared from [3-(3-benzyl-8-chlorocinnolin-4-yl)phenyl]amine and 3-methyl-benzo[b]thiophene-2-carbaldehyde according to the procedure of Step 5 Example 6. MS (ES) m/z 492.2.

Sources & evidence

ORD record
ord-7f7bf5e4cbb2419ebe9a7f1a6e525c4f
Source dataset
uspto-grants-2010_04
Patent number
US07700595B2

Reaction notes

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