3-(8-Chloro-3-phenyl-cinnolin-4-yl)-phenylamine → HCID 11854825, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[N:9][C:8]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[C:7]2[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1.[F:25][C:26]([F:39])([F:38])[C:27]1[C:35]2[CH:34]=[C:33]([CH:36]=O)[S:32][C:31]=2[CH:30]=[CH:29][CH:28]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[N:9][C:8]([C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)=[C:7]2[C:18]1[CH:19]=[C:20]([NH:24][CH2:36][C:33]2[S:32][C:31]3[CH:30]=[CH:29][CH:28]=[C:27]([C:26]([F:38])([F:25])[F:39])[C:35]=3[CH:34]=2)[CH:21]=[CH:22][CH:23]=1Participants
3
Procedure
The title compound was prepared from 3-(8-chloro-3-phenyl-cinnolin-4-yl)-phenylamine and 4-trifluoromethyl-benzo[b]thiophene-2-carbaldehyde according the procedure of Example 5 Step 5. MS (ESI) m/z 546.
Sources & evidence
- ORD record
- ord-9f3f0c466a38434fa1080afc9e4a7b7d
- Source dataset
- uspto-grants-2010_04
- Patent number
- US07700595B2
Reaction notes
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