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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 643335Generated: October 30, 2026

1-(Bromomethyl)-3-(trifluoromethyl)benzene → 3-Benzyl-8-chloro-4-(3-{[3-(trifluoromethyl)benzyl]oxy}phenyl)cinnoline

https://huagongshe.com/reaction/643335

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-3-(trifluoromethyl)benzeneHCID 123061—
Reactant3-(8-Chloro-3-phenylcinnolin-4-yl)phenolHCID 11856439—
Product3-Benzyl-8-chloro-4-(3-{[3-(trifluoromethyl)benzyl]oxy}phenyl)cinnolineHCID 11854315—

Reaction Steps

The title compound was prepared from 3-(8-chloro-3-phenyl-cinnolin-4-yl)-phenol and 3-trifluoromethylbenzyl bromide according the procedure of Example 14. MS (ES) m/z 504.8.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07700595B2
Source datasetuspto-grants-2010_04
ORD IDord-7604c97c1cb14bf8996dfd6ac2c85cab
Source noteuspto-grants-2010_04