7-Bromo-4-methoxy-1H-indole → 7-bromo-4-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

HRID 643407Notes

Reaction equation

HRID 643407 reaction equation
ClC1C=CC=C2C=1NC([B:11]1[O:15][C:14]([CH3:17])([CH3:16])[C:13]([CH3:19])([CH3:18])[O:12]1)=C2.[Br:20][C:21]1[CH:22]=[CH:23][C:24]([O:30][CH3:31])=[C:25]2[C:29]=1[NH:28][CH:27]=[CH:26]2>>[Br:20][C:21]1[CH:22]=[CH:23][C:24]([O:30][CH3:31])=[C:25]2[C:29]=1[NH:28][C:27]([B:11]1[O:15][C:14]([CH3:17])([CH3:16])[C:13]([CH3:19])([CH3:18])[O:12]1)=[CH:26]2

Participants

3

Reactant 2

HCID 36954997-Bromo-4-methoxy-1H-indoleHCID 532172117-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-indole

Product 1

HCID 591331437-bromo-4-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Procedure

Prepared according to a procedure analogous to that described for 7-chloro-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole using 7-bromo-4-methoxy-1H-indole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-654f5175f8cb4fd4ab86d38d29d2650d
Source dataset
uspto-grants-2010_04
Patent number
US07700594B2

Reaction notes

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