(3-Ethoxycarbonylphenyl)boronic acid → HCID 57880483, compound

HRID 643538Notes

Reaction equation

HRID 643538 reaction equation
FC(F)(F)S(O[C:7]1[CH:8]([CH3:20])[CH2:9][N:10]([CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:11][CH:12]=1)(=O)=O.[CH2:23]([O:25][C:26]([C:28]1[CH:29]=[C:30](B(O)O)[CH:31]=[CH:32][CH:33]=1)=[O:27])[CH3:24]>>[CH2:13]([N:10]1[CH2:11][CH:12]=[C:7]([C:32]2[CH:33]=[C:28]([CH:29]=[CH:30][CH:31]=2)[C:26]([O:25][CH2:23][CH3:24])=[O:27])[CH:8]([CH3:20])[CH2:9]1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 3249312(3-Ethoxycarbonylphenyl)boronic acidHCID 57880548HCID 57880548, compound2×

Product 1

HCID 57880483HCID 57880483, compound

Procedure

Ethyl 3-(1-benzyl-3-methyl-1,2,3,6-tetrahydropyridin-4-yl)benzoate was synthesized as described for INTERMEDIATE 6 (step A) using 1-benzyl-3-methyl-1,2,3,6-tetrahydropyridin-4-yl trifluoromethanesulfonate and [3-(ethoxycarbonyl)phenyl]boronic acid as starting materials.

Sources & evidence

ORD record
ord-a0bb6fca9f0545e99bc9ec50ebccc383
Source dataset
uspto-grants-2010_04
Patent number
US07700591B2

Reaction notes

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