HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-[3-(benzyloxy)-2-methyl-3-oxopropyl]piperidine-1-carboxylate → Benzyl 2-methyl-3-piperidin-4-ylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-[3-(benzyloxy)-2-methyl-3-oxopropyl]piperidine-1-carboxylate | HCID 59261045 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Benzyl 2-methyl-3-piperidin-4-ylpropanoate | HCID 59261012 | — |
Reaction Steps
tert-Butyl 4-[3-(benzyloxy)-2-methyl-3-oxopropyl]piperidine-1-carboxylate was dissolved in 5 mL of anhydrous 4N HCl in dioxane and stirred at rt for 1 h. The reaction mixture was concentrated to afford benzyl 2-methyl-3-piperidin-4-ylpropanoate. ESI-MS calc. for C16H23NO2: 261; Found: 262 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700591B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-1d168ef3f5354920b536dce124dd1a36 |
| Source note | uspto-grants-2010_04 |