HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 11750889, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Phenylboronic Acid | HCID 66827 | — |
| Reactant | Water ethanol | HCID 19096565 | — |
| Reactant | HCID 59262884 | HCID 59262884 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | HCID 11750889 | HCID 11750889 | — |
Reaction Steps
To the 3-(8-Bromo-5,6-dihydro-thieno[2,3-h]quinazolin-2-ylamino)-benzenesulfonamide (200 mg, 0.46 mmol) in a 10 mL microwave reaction tube was added Phenyl boronic acid (56 mg, 0.46 mmol), 2M Na2CO3(aq) (920 μL, 1.84 mmol), Pd(PPh3)4 (5.3 mg, 0.0046 mmol), 3:4 EtOH/H2O (1.5 mL) and DME (2.5 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700609B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-af12b5a3e68040979ef8ed4ab4002893 |
| Source note | uspto-grants-2010_04 |