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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 643783Generated: October 25, 2026

Methyl 3-(bromomethyl)benzoate → 3-(4'-Methyl-biphenyl-4-yloxymethyl)-benzoic acid

https://huagongshe.com/reaction/643783

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-(bromomethyl)benzoateHCID 517981—
Reactant4-(4-Methylphenyl)phenolHCID 1382789—
Product3-(4'-Methyl-biphenyl-4-yloxymethyl)-benzoic acidHCID 11162933—

Reaction Steps

3-(4′-Methyl-biphenyl-4-yloxymethyl)-benzoic acid was prepared using general procedure A from 4′-methyl-biphenyl-4-ol (purchased from Maybridge plc, Tintagel, Cornwall, UK or from Intermediate 5) and 3-(bromomethyl)benzoic acid methyl ester (available from Lancaster Synthesis Ltd., Morcambe, Lancashire, UK). Yield: 66 mg. Mass spectrum (ES) MH+=319.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07700632B2
Source datasetuspto-grants-2010_04
ORD IDord-b53fb4bcfa214125815196915a3e770b
Source noteuspto-grants-2010_04