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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 643796Generated: October 30, 2026

Methyl 5-(chloromethyl)-2-furoate → 5-(2'-Nitro-biphenyl-4-yloxymethyl)-furan-2-carboxylic acid

https://huagongshe.com/reaction/643796

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 5-(chloromethyl)-2-furoateHCID 75065—
Reactant4-Hydroxy-2'-nitrobiphenylHCID 15541112—
Product5-(2'-Nitro-biphenyl-4-yloxymethyl)-furan-2-carboxylic acidHCID 11405035—

Reaction Steps

5-(2′-Nitro-biphenyl-4-yloxymethyl)-furan-2-carboxylic acid was prepared using general procedure A from 4-hydroxy-2′-nitrobiphenyl (available from TCI America, Portland, Oreg.) and 5-chloromethylfuran-2-carboxylic acid methyl ester (available from Aldrich, Milwaukee, Wis., or from Maybridge plc, Tintagel, UK). Yield: 82 mg. Mass spectrum (ES) MH+=340.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07700632B2
Source datasetuspto-grants-2010_04
ORD IDord-3c8bb584941e4a049d53b1f31c280f49
Source noteuspto-grants-2010_04