Water → HCID 66750509, compound

Participants

Reaction Conditions

Reaction Steps

3-Bromonaphthalene-2,7-diol (1.40 g, 5.88 mmol) is dissolved in 20 mL of DMF. Potassium carbonate (2.44 g, 17.6 mmol) is added and the mixture is heated to 60° C. Benzyl bromide (2.10 mL, 17.64 mmol) is added and heating is continued for 5 h, after which time the reaction is poured into water and extracted with MTBE. The combined organics are dried and evaporated to afford 3,6-bis-benzyloxy-2-bromonaphthalene as a brown solid, which is of sufficient purity to take on to the next step.

Provenance & Evidence