HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyano-1-butyne → (E)-5-[6-Hydroxy-7-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-naphthalen-2-yl]-pent-4-enenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyano-1-butyne | HCID 140560 | — |
| Reactant | 5-(7-Bromo-3-hydroxynaphthalen-2-yl)-1,1-dioxo-1,2,5-thiadiazolidin-3-one | HCID 17751761 | — |
| Product | (E)-5-[6-Hydroxy-7-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)-naphthalen-2-yl]-pent-4-enenitrile | HCID 17751395 | — |
Reaction Steps
The title compound is prepared analogously to Example 8, step A, beginning with pent-4-ynenitrile and 5-(7-bromo-3-hydroxynaphthalen-2-yl)-1,1-dioxo-1,2,5-thiadiazolidin-3-one (Example 3, step E): Retention time=0.91 min (Method A); (M−H)−=356.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700633B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-9b367292da764bd19a1406e1e66a2a4e |
| Source note | uspto-grants-2010_04 |