Triacetoxyperiodinane → HCID 66750620, compound

Participants

Reaction Steps

A solution of 5-(3-benzyloxy-6-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-2-benzyloxymethyl-1,1-dioxo-1,2,5-thiadiazolidin-3-one (87.6 mg, 0.17 mmol) in DCM (3 mL) is added to a suspension of Dess-Martin reagent (80 mg, 0.19 mmol) in DCM (1 mL). The mixture is stirred at RT for 30 min and filtered through Celite. The filtrate is concentrated and purified by chromatography to give the title compound as an oil: 1H NMR (CDCl3) δ 2.54 (t, J=7 Hz, 2H), 3.01 (t, J=7 Hz, 2H), 3.55 (s, 2H), 4.44 (s, 2H), 4.57 (s, 2H), 5.03 (s, 2H), 5.8 (s, 2H), 6.82 (s, 1H), 7.28-7.36 (m, 11H); (M+NH4)+=524.

Provenance & Evidence