Peracetic Acid → HCID 178474496, compound

HRID 643979Notes

Reaction equation

HRID 643979 reaction equation
[C:1]([NH:4][C:5](=[N:7]/[N:8]=[CH:9]/[C:10]1[CH:11]=[C:12]2[C:18]([CH3:19])=[N:17][NH:16][C:13]2=[N:14][CH:15]=1)[SH:6])(=[O:3])[CH3:2].C(OO)(=O)C>C(O)(=O)C>[CH3:19][C:18]1[C:12]2[C:13](=[N:14][CH:15]=[C:10]([C:9]3[S:6][C:5]([NH:4][C:1](=[O:3])[CH3:2])=[N:7][N:8]=3)[CH:11]=2)[NH:16][N:17]=1

Participants

4

Reactant 2

HCID 6585Peracetic AcidHCID 178475126HCID 178475126, compound

Product 1

HCID 178474496HCID 178474496, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
60 °C

Procedure

The starting material 1-acetyl-3-((E)-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)methyleneamino)isothiourea (5 g) (80 mg, 0.22 mmol) was taken up in 5 ml acetic acid and 1.2 ml peracetic acid in a round bottom flask. The mixture was heated to 60° C. After 15 min, the product was precipitated out. The solid was filtered off and washed with ether (50 ml). The yield for this reaction was quantitative and the product was used for the next step without further purification.

Workup

  1. customthe product was precipitated out
  2. filtrationThe solid was filtered off
  3. washwashed with ether (50 ml)
  4. customThe yield for this reaction
  5. customthe product was used for the next step without further purification

Sources & evidence

ORD record
ord-0509a1a25b5c413fbe617f59f69f09e9
Source dataset
uspto-grants-2010_04
Patent number
US07700636B2

Reaction notes

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