HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Cyclohexylmethoxy)-5-methyl-2-nitropyridine → 3-(Cyclohexylmethoxy)-5-methylpyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Cyclohexylmethoxy)-5-methyl-2-nitropyridine | HCID 86713406 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(Cyclohexylmethoxy)-5-methylpyridin-2-amine | HCID 86713407 | 87.1% |
Reaction Steps
To a solution of 1.8 g of 3-(cyclohexylmethoxy)-5-methyl-2-nitropyridine in 16 ml of THF was added 325 mg of 10% palladium-carbon (wet), followed by stirring for 3 hours under a hydrogen atmosphere. The reaction mixture was filtered over Celite and the solvent was then evaporated under reduced pressure to obtain 1.38 g of 3-(cyclohexylmethoxy)-5-methylpyridin-2-amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447090B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-2a0b295554fe4d9f8067e93a213a0322 |
| Source note | uspto-grants-2016_09 |