HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Cladrin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Boron trifluoride etherate | HCID 8000 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 1-(2,4-Dihydroxyphenyl)-2-(3,4-dimethoxyphenyl)ethanone | HCID 689038 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Cladrin | HCID 5748605 | — |
Reaction Steps
In a similar manner to Example 2.1 above, 1-(2,4-dihydroxyphenyl)-2-(3,4-dimethoxy-phenyl)-ethanone dissolved in DMF had added boron trifluoride diethyl etherate followed by methanesulfonyl chloride in DMF. Addition of water to the reaction mixture afforded 3-(3,4-dimethoxyphenyl)-7-hydroxychromen-4-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700644B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-fbfba911c8af4d449508660be8352281 |
| Source note | uspto-grants-2010_04 |