HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 644160Generated: October 29, 2026
4-Chloroaniline → 2-amino-N-(4-chlorophenyl)benzamide
https://huagongshe.com/reaction/644160
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Chloroaniline | HCID 7812 | — |
| Reactant | Isatoic Anhydride | HCID 8359 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-amino-N-(4-chlorophenyl)benzamide | HCID 670472 | — |
Reaction Steps
A mixture of 20 g (123 mmol) isatoic anhydride (formed by treating anthranilic acid with phosgene) and 15.64 g (123 mmol) 4-chloroaniline was heated at 120° C. for 2 hours. The reaction was cooled to room temperature, mixed with CH2Cl2 and filtered.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07700628B2 |
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| Source dataset | uspto-grants-2010_04 |
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| ORD ID | ord-f105896d76a74ce7a459cb137e629911 |
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| Source note | uspto-grants-2010_04 |
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