HRID644185

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)OC(=O)N1CCC(Oc2cc(C(C)(C)C)ccc2C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)CC1

HCID68532395

未命名化合物

结构：CC(C)(C)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c(OC2CCNCC2)c1.Cl

HCID68534241

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CCC(Oc2cc(C(C)(C)C)ccc2C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)CC1.Cl

HCID68532394

未命名化合物

PROCEDURE

实验过程

By methods substantially equivalent to those described in Example 16-G, 2-[4-(tert-butyl)-2-(piperidin-4-yloxy)benzoylamino]-N-(5-chloropyridin-2-yl)-5-chloro-benzamide hydrochloride (0.326 g, 88%) was prepared from 2-[4-(tert-butyl)-2-(1-Boc-piperidin-4-yloxy)benzoylamino]-5-chloro-N-(5-chloropyridin-2-yl)benzamide.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8ae5ecf352ff45249c9a805cf9f3d9f2
来源数据集: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07700628B2
来源说明: uspto-grants-2010_04

反应 SMILES

Cl.C(C1C=CC(C(NC2C=CC(Cl)=CC=2C(NC2C=CC([Cl:24])=CN=2)=O)=O)=C(OC2CCNCC2)C=1)(C)(C)C.[C:39]([C:43]1[CH:68]=[CH:67][C:46]([C:47]([NH:49][C:50]2[CH:65]=[CH:64][C:63]([Cl:66])=[CH:62][C:51]=2[C:52]([NH:54][C:55]2[CH:60]=[CH:59][C:58]([Cl:61])=[CH:57][N:56]=2)=[O:53])=[O:48])=[C:45]([O:69][CH:70]2[CH2:75][CH2:74][N:73]([C:76]([O:78][C:79]([CH3:82])([CH3:81])[CH3:80])=[O:77])[CH2:72][CH2:71]2)[CH:44]=1)([CH3:42])([CH3:41])[CH3:40]>>[ClH:24].[C:39]([C:43]1[CH:68]=[CH:67][C:46]([C:47]([NH:49][C:50]2[CH:65]=[CH:64][C:63]([Cl:66])=[CH:62][C:51]=2[C:52]([NH:54][C:55]2[CH:60]=[CH:59][C:58]([Cl:61])=[CH:57][N:56]=2)=[O:53])=[O:48])=[C:45]([O:69][CH:70]2[CH2:71][CH2:72][N:73]([C:76]([O:78][C:79]([CH3:82])([CH3:81])[CH3:80])=[O:77])[CH2:74][CH2:75]2)[CH:44]=1)([CH3:42])([CH3:40])[CH3:41]