Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | HCID 68532710 | HCID 68532710 | — |
| Product | HCID 57860904 | HCID 57860904 | 83% |
Reaction Steps
Using methods substantially equivalent to those described in example 4-F, except that the reaction was heated to 80° C., 2-[2-(3-tert-butoxycarbonylamino-2-methyl-propoxy)-4-(pyrrolidin-1-yl)benzoylamino]-N-(5-chloropyridin-2-yl)benzamide (427 mg, 0.70 mmol, 83%) was prepared from 2-[2-(3-tert-butoxycarbonylamino-2-methyl-propoxy)-4-fluorobenzoylamino]-N-(5-chloropyridin-2-yl)benzamide and pyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07700628B2 |
|---|
| Source dataset | uspto-grants-2010_04 |
|---|
| ORD ID | ord-50a237de2e8c4e21b9d03cf7560357ba |
|---|
| Source note | uspto-grants-2010_04 |
|---|
