Methanol → HCID 68534944, compound

Participants

Reaction Steps

Using methods substantially equivalent to those described in Example 21-D, methyl 2-(1-tert-butoxycarbonylpiperidin-4-yloxy)-4-(morpholin-4-yl)benzoate (2.40 g, 5.71 mmol), lithium hydroxide monohydrate (605 mg, 15.1 mmol), and 2:1 (10% water in tetrahydrofuran):methanol (75 mL) afforded 2.16 g (93%) of the title compound; which was used without further purification.

Provenance & Evidence