2-amino-N-(5-chloropyridin-2-yl)-5-fluorobenzamide → 2-[2-[2-(tert-Butoxycarbonylamino)ethoxy]-4-(methylthio)benzoylamino]-N-(5-chloropyridin-2-yl)-5-fluorobenzamide

Participants

Role	Name	HCID	Charge
Reactant	2-amino-N-(5-chloropyridin-2-yl)-5-fluorobenzamide	HCID 21906315	—
Reactant	2-(2-Tert-butoxycarbonylaminoethoxy)-4-(methylthio)benzoic acid	HCID 57936572	—
Product	2-[2-[2-(tert-Butoxycarbonylamino)ethoxy]-4-(methylthio)benzoylamino]-N-(5-chloropyridin-2-yl)-5-fluorobenzamide	HCID 68533843	—

Reaction Steps

2-[2-[2-(tert-Butoxycarbonylamino)ethoxy]-4-(methylthio)benzoylamino]-N-(5-chloropyridin-2-yl)-5-fluorobenzamide was prepared by methods described in Example 4-E from 2-[2-[2-(tert-butoxycarbonylamino)ethoxy]-4-(methylthio)benzoic acid and N-(5-chloropyridin-2-yl)-2-amino-5-fluorobenzamide (2.80 g, 89%).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07700628B2
Source dataset	uspto-grants-2010_04
ORD ID	ord-93146a2a51b94d2aac2e9ef118ff14b5
Source note	uspto-grants-2010_04