Methyl 4-methoxysalicylate → HCID 68530524, compound

HRID 644267Notes

Reaction equation

HRID 644267 reaction equation
C(O[N:6]1[CH2:11][CH2:10][CH:9]([O:12][C:13]2[CH:22]=[C:21]([O:23][CH3:24])[CH:20]=[CH:19][C:14]=2[C:15]([O:17][CH3:18])=[O:16])[CH2:8][C:7]1=C=O)(C)(C)C.OC1C=C(OC)C=CC=1C(OC)=O.OC1CCN([C:47]([O:49][C:50]([CH3:53])([CH3:52])[CH3:51])=[O:48])CC1>>[C:50]([O:49][C:47]([N:6]1[CH2:7][CH2:8][CH:9]([O:12][C:13]2[CH:22]=[C:21]([O:23][CH3:24])[CH:20]=[CH:19][C:14]=2[C:15]([O:17][CH3:18])=[O:16])[CH2:10][CH2:11]1)=[O:48])([CH3:53])([CH3:52])[CH3:51]

Participants

4

Reactant 3

HCID 79523Methyl 4-methoxysalicylateHCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylateHCID 86634214HCID 86634214, compound

Product 1

HCID 68530524HCID 68530524, compound

Procedure

Using a procedure similar to that used in Example 21-C, methyl 2-(1-tert-butoxy-carbonylpiperidin-4-yloxy)-4-methoxybenzoate (10.38 g, 71%) was prepared from methyl 2-hydroxy-4-methoxybenzoate and 4-hydroxy-1-tert-butoxycarbonylpiperidine.

Sources & evidence

ORD record
ord-ca03b1a247d143f98281b8267208c846
Source dataset
uspto-grants-2010_04
Patent number
US07700628B2

Reaction notes

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