HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-amino-N-(5-chloropyridin-2-yl)-4-methoxycarbonylbenzamide → n-(5-Chloropyridin-2-yl)-4-methoxycarbonyl-2-[4-methylthio-2-(3-(t-butoxy-carbonylamino)propoxy)benzoylamino]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-amino-N-(5-chloropyridin-2-yl)-4-methoxycarbonylbenzamide | HCID 21906318 | — |
| Reactant | 2-(3-Tert-butoxycarbonylaminopropoxy)-4-(methylthio)benzoic acid | HCID 57936540 | — |
| Product | n-(5-Chloropyridin-2-yl)-4-methoxycarbonyl-2-[4-methylthio-2-(3-(t-butoxy-carbonylamino)propoxy)benzoylamino]benzamide | HCID 68530427 | 50% |
Reaction Steps
Using a procedure analogous to Example 4-E, N-(5-chloropyridin-2-yl)-4-methoxycarbonyl-2-aminobenzamide and 4-(methylthio)-2-(3-(t-butoxycarbonylamino)-propoxy)benzoic acid gave the title compound as a white solid (12 g, 50%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700628B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-184d6c2284f7425b92ad80620018c07a |
| Source note | uspto-grants-2010_04 |