反应详情

The methyl 4-benzyloxy-2-(1-tert-butoxycarbonylpiperidin-4-yloxy)benzoate (12.8 g) was dissolved in EtOH (135 mL). 10% Pd/C catalyst (1.3 g) was added and the reaction was placed under an H2 atmosphere (4.1 bar) for 4 h at room temperature. The catalyst was filtered and the ethanol was removed in vacuo to give 9.15 g (89.7%) of a white foam.

1. customfor 4 h
2. customat room temperature
3. filtrationThe catalyst was filtered
4. customthe ethanol was removed in vacuo