Ethyl(4-piperidin-4-yl-piperazin-1-yl)-acetate → ethyl {4-[1-((R)-3-(3,4-diethyl-phenyl)-2-{[4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidine-1-carbonyl]-amino}-propionyl)-piperidin-4-yl]-piperazin-1-yl}-acetate

Participants

Role	Name	HCID	Charge
Reactant	Ethyl(4-piperidin-4-yl-piperazin-1-yl)-acetate	HCID 57848475	—
Reactant	(R)-3-(3,4-diethyl-phenyl)-2-{[4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidine-1-carbonyl]-amino}-propionic acid	HCID 68579001	—
Product	ethyl {4-[1-((R)-3-(3,4-diethyl-phenyl)-2-{[4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidine-1-carbonyl]-amino}-propionyl)-piperidin-4-yl]-piperazin-1-yl}-acetate	HCID 10485087	—

Reaction Steps

Prepared analogously to Example 34 from (R)-3-(3,4-diethyl-phenyl)-2-{[4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidine-1-carbonyl]-amino}-propionic acid and ethyl (4-piperidin-4-yl-piperazin-1-yl)-acetate

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07700589B2
Source dataset	uspto-grants-2010_04
ORD ID	ord-9a2a281469df4782b4b2e3ac6da11e9c
Source note	uspto-grants-2010_04