3-(Piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one → HCID 68579984, compound

HRID 644380Notes

Reaction equation

HRID 644380 reaction equation
[CH2:1]([C:3]1[CH:4]=[C:5]([CH2:11][C:12]([C:22]([O:24][CH2:25][CH3:26])=[O:23])([C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH2:13][C:14](O)=[O:15])[CH:6]=[CH:7][C:8]=1[CH2:9][CH3:10])[CH3:2].[NH:27]1[CH2:32][CH2:31][CH:30]([N:33]2[CH2:42][C:41]3[C:36](=[CH:37][CH:38]=[CH:39][CH:40]=3)[NH:35][C:34]2=[O:43])[CH2:29][CH2:28]1>>[CH2:1]([C:3]1[CH:4]=[C:5]([CH:6]=[CH:7][C:8]=1[CH2:9][CH3:10])[CH2:11][C:12]([CH2:13][C:14](=[O:15])[N:27]1[CH2:28][CH2:29][CH:30]([N:33]2[CH2:42][C:41]3[C:36](=[CH:37][CH:38]=[CH:39][CH:40]=3)[NH:35][C:34]2=[O:43])[CH2:31][CH2:32]1)([C:17]([O:19][CH2:20][CH3:21])=[O:18])[C:22]([O:24][CH2:25][CH3:26])=[O:23])[CH3:2]

Participants

3

Reactant 2

HCID 110425973-(Piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-oneHCID 22184567HCID 22184567, compound

Product 1

HCID 68579984HCID 68579984, compound

Procedure

Prepared analogously to Example 76c) from 4-(3,4-diethyl-phenyl)-3,3-bis-ethoxycarbonyl-butanoic acid and 3-piperidin-4-yl-3,4-dihydro-1H-quinazolin-2-one.

Sources & evidence

ORD record
ord-ae0a031ade2143ccb65ca26cd391fe6f
Source dataset
uspto-grants-2010_04
Patent number
US07700589B2

Reaction notes

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