HRID644381

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID795707

1-Methyl-4-(piperidin-4-yl)piperazine

C10H21N3

结构：CCc1ccc(CC(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)C(=O)O)cc1CC

HCID68578887

未命名化合物

PRODUCTS

生成物

结构：CCc1ccc(CC(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCN(C)CC3)CC2)cc1CC

HCID59260997

未命名化合物

PROCEDURE

实验过程

Prepared analogously to Example 76e) from 2-(3,4-diethyl-benzyl)-4-oxo-4-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-butanoic acid and 1-methyl-4-piperidin-4-yl-piperazine

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-636e3824e7c04b40b0bf69318ebc05ca
来源数据集: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07700589B2
来源说明: uspto-grants-2010_04

反应 SMILES

[CH2:1]([C:3]1[CH:4]=[C:5]([CH:31]=[CH:32][C:33]=1[CH2:34][CH3:35])[CH2:6][CH:7]([CH2:11][C:12](=[O:30])[N:13]1[CH2:18][CH2:17][CH:16]([N:19]2[CH2:28][C:27]3[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=3)[NH:21][C:20]2=[O:29])[CH2:15][CH2:14]1)[C:8](O)=[O:9])[CH3:2].[CH3:36][N:37]1[CH2:42][CH2:41][N:40]([CH:43]2[CH2:48][CH2:47][NH:46][CH2:45][CH2:44]2)[CH2:39][CH2:38]1>>[CH2:1]([C:3]1[CH:4]=[C:5]([CH:31]=[CH:32][C:33]=1[CH2:34][CH3:35])[CH2:6][CH:7]([CH2:11][C:12]([N:13]1[CH2:18][CH2:17][CH:16]([N:19]2[CH2:28][C:27]3[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=3)[NH:21][C:20]2=[O:29])[CH2:15][CH2:14]1)=[O:30])[C:8]([N:46]1[CH2:45][CH2:44][CH:43]([N:40]2[CH2:39][CH2:38][N:37]([CH3:36])[CH2:42][CH2:41]2)[CH2:48][CH2:47]1)=[O:9])[CH3:2]