3-(Piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one → HCID 68578999, compound

HRID 644383Notes

Reaction equation

HRID 644383 reaction equation
[CH2:1]([O:3][C:4]([C:6]([C:22]([O:24][CH2:25][CH3:26])=[O:23])([CH2:11][C:12]1[CH:21]=[CH:20][C:19]2[CH2:18][CH2:17][CH2:16][CH2:15][C:14]=2[CH:13]=1)[CH2:7][C:8]([OH:10])=O)=[O:5])[CH3:2].[NH:27]1[CH2:32][CH2:31][CH:30]([N:33]2[CH2:42][C:41]3[C:36](=[CH:37][CH:38]=[CH:39][CH:40]=3)[NH:35][C:34]2=[O:43])[CH2:29][CH2:28]1>>[O:10]=[C:8]([N:27]1[CH2:28][CH2:29][CH:30]([N:33]2[CH2:42][C:41]3[C:36](=[CH:37][CH:38]=[CH:39][CH:40]=3)[NH:35][C:34]2=[O:43])[CH2:31][CH2:32]1)[CH2:7][C:6]([CH2:11][C:12]1[CH:13]=[CH:14][C:15]2[CH2:16][CH2:17][CH2:18][CH2:19][C:20]=2[CH:21]=1)([C:22]([O:24][CH2:25][CH3:26])=[O:23])[C:4]([O:3][CH2:1][CH3:2])=[O:5]

Participants

3

Reactant 2

HCID 110425973-(Piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-oneHCID 68579185HCID 68579185, compound

Product 1

HCID 68578999HCID 68578999, compound

Procedure

Prepared analogously to Example 76c) from 3,3-bis-ethoxycarbonyl-4-(5,6,7,8-tetrahydro-naphthalen-2-yl)-butanoic acid and 3-piperidin-4-yl-3,4-dihydro-1H-quinazolin-2-one.

Sources & evidence

ORD record
ord-13707f55dd344f08b3841ca8f23857d6
Source dataset
uspto-grants-2010_04
Patent number
US07700589B2

Reaction notes

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