3-(Piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one → HCID 68579275, compound

HRID 644385Notes

Reaction equation

HRID 644385 reaction equation
[CH2:1]([O:3][C:4]([C:6]([C:21]([O:23][CH2:24][CH3:25])=[O:22])([CH2:11][C:12]1[CH:13]=[C:14]2[C:18](=[CH:19][CH:20]=1)[CH2:17][CH2:16][CH2:15]2)[CH2:7][C:8]([OH:10])=O)=[O:5])[CH3:2].[NH:26]1[CH2:31][CH2:30][CH:29]([N:32]2[CH2:41][C:40]3[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=3)[NH:34][C:33]2=[O:42])[CH2:28][CH2:27]1>>[CH2:17]1[C:18]2[C:19](=[CH:20][C:12]([CH2:11][C:6]([CH2:7][C:8](=[O:10])[N:26]3[CH2:27][CH2:28][CH:29]([N:32]4[CH2:41][C:40]5[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=5)[NH:34][C:33]4=[O:42])[CH2:30][CH2:31]3)([C:21]([O:23][CH2:24][CH3:25])=[O:22])[C:4]([O:3][CH2:1][CH3:2])=[O:5])=[CH:13][CH:14]=2)[CH2:15][CH2:16]1

Participants

3

Reactant 2

HCID 110425973-(Piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-oneHCID 68579277HCID 68579277, compound

Product 1

HCID 68579275HCID 68579275, compound

Procedure

Prepared analogously to Example 76c) from 3,3-bis-ethoxycarbonyl-4-indan-5-yl-butanoic acid and 3-piperidin-4-yl-3,4-dihydro-1H-quinazolin-2-one.

Sources & evidence

ORD record
ord-d1c66e71922846b087a404a9b9fe733c
Source dataset
uspto-grants-2010_04
Patent number
US07700589B2

Reaction notes

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