2-Acetoxybenzoyl chloride → HCID 3387363, compound

HRID 644398Notes

Reaction equation

HRID 644398 reaction equation
[CH3:1][C:2]([O:4][C:5]1[C:10]([C:11](Cl)=[O:12])=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:3].[NH2:14][C:15]1[S:16][C:17]([C:20]([F:23])([F:22])[F:21])=[N:18][N:19]=1>>[C:2]([O:4][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:10]=1[C:11]([NH:14][C:15]1[S:16][C:17]([C:20]([F:23])([F:22])[F:21])=[N:18][N:19]=1)=[O:12])(=[O:3])[CH3:1]

Participants

3

Reactant 2

HCID 796682-Acetoxybenzoyl chlorideHCID 826341,3,4-Thiadiazol-2-amine, 5-(trifluoromethyl)-

Product 1

HCID 3387363HCID 3387363, compoundYield 51.1%

Procedure

Using O-acetylsalicyloyl chloride and 2-amino-5-(trifluoromethyl)-1,3,4-thiadiazole as the raw materials, the same operation as the Example 2(1) gave the title compound.

Sources & evidence

ORD record
ord-615e9cd45e004361b150303cfa3c5e73
Source dataset
uspto-grants-2010_04
Patent number
US07700655B2

Reaction notes

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