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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 644424Generated: October 30, 2026

Piperidine → 2-Benzyloxy-N-[3,5-bis(trifluoromethyl)phenyl]-5-(piperidine-1-carbonyl)benzamide

https://huagongshe.com/reaction/644424

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
Reactant4-benzyloxy-N-[3,5-bis(trifluoromethyl)phenyl]isophthalamic acidHCID 86602678—
Product2-Benzyloxy-N-[3,5-bis(trifluoromethyl)phenyl]-5-(piperidine-1-carbonyl)benzamideHCID 1786016556.4%

Reaction Steps

Using 4-benzyloxy-N-[3,5-bis(trifluoromethyl)phenyl]isophthalamic acid (compound of Example 84(2)) and piperidine as the raw materials, the same operation as the Example 84(3) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07700655B2
Source datasetuspto-grants-2010_04
ORD IDord-a58db2a2a43a48dfb273f8235d14ae3c
Source noteuspto-grants-2010_04