HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Benzylpiperidine → 2-Benzyloxy-5-(4-benzylpiperidine-1-carbonyl)-N-[3,5-bis(trifluoromethyl)phenyl]-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Benzylpiperidine | HCID 31738 | — |
| Reactant | 4-benzyloxy-N-[3,5-bis(trifluoromethyl)phenyl]isophthalamic acid | HCID 86602678 | — |
| Product | 2-Benzyloxy-5-(4-benzylpiperidine-1-carbonyl)-N-[3,5-bis(trifluoromethyl)phenyl]-benzamide | HCID 23069964 | 76.7% |
Reaction Steps
Using 4-benzyloxy-N-[3,5-bis(trifluoromethyl)phenyl]isophthalamic acid (compound of Example 84(2)) and 4-benzylpiperidine as the raw materials, the same operation as the Example 84(3) gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700655B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-13b4ab2763254451b742e5b4e7a634dd |
| Source note | uspto-grants-2010_04 |