Benzenamine, 3,5-bis(trifluoromethyl)- → HCID 136026712, compound

HRID 644459Notes

Reaction equation

HRID 644459 reaction equation
[Cl:1][C:2]1[CH:9]=[C:6]([CH:7]=O)[C:5]([OH:10])=[CH:4][CH:3]=1.[F:11][C:12]([F:25])([F:24])[C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([C:20]([F:23])([F:22])[F:21])[CH:19]=1)[NH2:16]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:10])=[C:6]([CH:7]=[N:16][C:15]2[CH:17]=[C:18]([C:20]([F:21])([F:22])[F:23])[CH:19]=[C:13]([C:12]([F:11])([F:24])[F:25])[CH:14]=2)[CH:9]=1

Participants

3

Reactant 2

HCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 124815-Chloro-salicylaldehyde

Product 1

HCID 136026712HCID 136026712, compoundYield 76.6%

Procedure

Using 5-chlorosalicylaldehyde and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the Example 14(1) gave the title compound.

Sources & evidence

ORD record
ord-60cf52adac4d4195af088118e408c60f
Source dataset
uspto-grants-2010_04
Patent number
US07700655B2

Reaction notes

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