3-Aminobenzamide → Benzamide,2-(acetyloxy)-n-[3-(aminocarbonyl)phenyl]-5-chloro-

HRID 644469Notes

Reaction equation

HRID 644469 reaction equation
[C:1]([O:4][C:5]1[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][C:6]=1[C:7]([OH:9])=O)(=[O:3])[CH3:2].[NH2:15][C:16]1[CH:17]=[C:18]([CH:22]=[CH:23][CH:24]=1)[C:19]([NH2:21])=[O:20]>>[C:1]([O:4][C:5]1[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][C:6]=1[C:7]([NH:15][C:16]1[CH:24]=[CH:23][CH:22]=[C:18]([C:19](=[O:20])[NH2:21])[CH:17]=1)=[O:9])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 16453-AminobenzamideHCID 28208132-(Acetyloxy)-5-chlorobenzoic acid

Product 1

HCID 23069937Benzamide,2-(acetyloxy)-n-[3-(aminocarbonyl)phenyl]-5-chloro-Yield 15.8%

Procedure

Using 2-acetoxy-5-chlorobenzoic acid and 3-aminobenzamide as the raw materials, the same operation as the Example 24 gave the title compound.

Sources & evidence

ORD record
ord-17683a8bc71849bcacc20b1d2f8aa908
Source dataset
uspto-grants-2010_04
Patent number
US07700655B2

Reaction notes

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