Ethanone, 1-(3,4-dichlorophenyl)- → 4-(3,4-Dichlorophenyl)-1,3-thiazol-2-amine

HRID 644476Notes

Reaction equation

HRID 644476 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9](=O)[CH3:10])[CH:5]=[CH:6][C:7]=1[Cl:8].[NH2:12][C:13]([NH2:15])=[S:14]>>[NH2:15][C:13]1[S:14][CH:10]=[C:9]([C:4]2[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=2)[N:12]=1

Participants

3

Reactant 2

HCID 75841Ethanone, 1-(3,4-dichlorophenyl)-HCID 2723790Thiourea

Product 1

HCID 6185364-(3,4-Dichlorophenyl)-1,3-thiazol-2-amineYield 77.8%

Procedure

Using 3′,4′-dichloroacetophenone and thiourea as the raw materials, the same operation as the Example 395(1) gave the title compound.

Sources & evidence

ORD record
ord-752602b229294cc0b5f5d115b8abdf1b
Source dataset
uspto-grants-2010_04
Patent number
US07700655B2

Reaction notes

Loading…