反应详情

2N Aqueous sodium hydroxide (5 mL) was added to a solution of methyl 2-methoxy-4-phenylbenzoate (410 mg, 1.69 mmol) in methanol (5 mL), and the mixture was refluxed for 1 hour. After the reaction mixture was cooled to room temperature, the solvent was evaporated under reduced pressure. 2N hydrochloric acid was added to the obtained residue and the separated crystal was filtered to give the title compound (371 mg, 96.0%) as a crude product.

1. temperaturethe mixture was refluxed for 1 hour
2. customthe solvent was evaporated under reduced pressure
3. addition2N hydrochloric acid was added to the obtained residue
4. filtrationthe separated crystal was filtered