Benzenamine, 3,5-bis(trifluoromethyl)- → N-[3,5-bis(trifluoromethyl)phenyl]-2-methoxy-4-phenylbenzamide

HRID 644485Notes

Reaction equation

HRID 644485 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=O.[F:18][C:19]([F:32])([F:31])[C:20]1[CH:21]=[C:22]([CH:24]=[C:25]([C:27]([F:30])([F:29])[F:28])[CH:26]=1)[NH2:23]>>[F:18][C:19]([F:31])([F:32])[C:20]1[CH:21]=[C:22]([NH:23][C:5](=[O:7])[C:4]2[CH:8]=[CH:9][C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[CH:11][C:3]=2[O:2][CH3:1])[CH:24]=[C:25]([C:27]([F:28])([F:30])[F:29])[CH:26]=1

Participants

3

Reactant 2

HCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 186874072-Methoxy-4-phenylbenzoic acid

Product 1

HCID 57459277N-[3,5-bis(trifluoromethyl)phenyl]-2-methoxy-4-phenylbenzamideYield 97.5%

Procedure

Using 2-methoxy-4-phenylbenzoic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the Example 16 gave the title compound.

Sources & evidence

ORD record
ord-1247f0844d224208a56bd5f85a1d9879
Source dataset
uspto-grants-2010_04
Patent number
US07700655B2

Reaction notes

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