HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2,5-Difluorophenyl)ethan-1-one → 4-(2,5-Difluorophenyl)-1,3-thiazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2,5-Difluorophenyl)ethan-1-one | HCID 74794 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Product | 4-(2,5-Difluorophenyl)-1,3-thiazol-2-amine | HCID 2064089 | 77.8% |
Reaction Steps
Using 2′,5′-difluoroacetophenone and thiourea as the raw materials, the same operation as the Example 395(1) gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700655B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-fef72665099a40caaa4b8b16b1184265 |
| Source note | uspto-grants-2010_04 |