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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 644488Generated: October 26, 2026

5-Chlorosalicylic Acid → 5-Chloro-N-[4-(2,5-difluorophenyl)-1,3-thiazol-2-yl]-2-hydroxybenzamide

https://huagongshe.com/reaction/644488

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chlorosalicylic AcidHCID 9447—
Reactant4-(2,5-Difluorophenyl)-1,3-thiazol-2-amineHCID 2064089—
Product5-Chloro-N-[4-(2,5-difluorophenyl)-1,3-thiazol-2-yl]-2-hydroxybenzamideHCID 5745927836.5%

Reaction Steps

Using 5-chlorosalicylic acid and 2-amino-4-(2,5-difluorophenyl)thiazole as the raw materials, the same operation as the Example 16 gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07700655B2
Source datasetuspto-grants-2010_04
ORD IDord-1896aa031a50424ab7d9e805c462890d
Source noteuspto-grants-2010_04