Potassium Carbonate → 5-Cyano-7-(4 cyanophenyl)-1-phenylbenzimidazole

Participants

Reaction Steps

This was prepared from 5-cyano-7-iodo-1-phenylbenzimidazole (173 mg, 0.5 mmol), toluene (3.0 ml), tetrakis(triphenylphosphine)palladium(0) (58 mg, 0.05 mmol), 4-cyanophenylboronic acid (74 mg, 0.5 mmol), ethanol (3.0 ml) and potassium carbonate (138 mg, 1.0 mmol) in a similar manner to 7-(3-acetamidophenyl)-5-cyano-1-phenylbenzimidazole. Purification by a similar procedure afforded the title compound (94 mg, 59%) m/z, 321.0 (M+H)+.

Provenance & Evidence