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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 644542Generated: October 30, 2026

1-(4-Methylpiperazin-1-yl)-3-(3-phenyl-6-trifluoromethyl-3H-benzimidazol-4-yl)prop-2-en-1-one → HCID 67485635, compound

https://huagongshe.com/reaction/644542

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Methylpiperazin-1-yl)-3-(3-phenyl-6-trifluoromethyl-3H-benzimidazol-4-yl)prop-2-en-1-oneHCID 67484930—
ReactantHCID 68679686HCID 68679686—
ProductHCID 67485635HCID 6748563560%

Reaction Steps

This was prepared from 3-(3-phenyl-trifluoromethyl-3H-benzimidazol-4-yl)acrylic acid methyl ester in a similar manner to 1-(4-methylpiperazin-1-yl)-3-(3-phenyl-6-trifluoromethyl-3H-benzimidazol-4-yl)prop-2-en-1-one to afford the title compound as a white solid (350 mg, 60%), m/z 402.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07700638B2
Source datasetuspto-grants-2010_04
ORD IDord-8c61a770602a442eae4eed8d021d9144
Source noteuspto-grants-2010_04