Tetrabutylammonium Fluoride → HCID 59263692, compound

HRID 644577Notes

Reaction equation

[Si]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:37]=[CH:38][C:39]=1[CH2:40][O:41][Si](C(C)(C)C)(C)C)[CH2:13][O:14][C:15]1[CH:16]=[C:17](/[C:21](/[CH2:35][CH3:36])=[CH:22]/[CH:23]=[CH:24]/[C:25]([C:31]([F:34])([F:33])[F:32])([OH:30])[C:26]([F:29])([F:28])[F:27])[CH:18]=[CH:19][CH:20]=1)(C(C)(C)C)(C)C.[F-].C([N+](CCCC)(CCCC)CCCC)CCC>>[OH:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:37]=[CH:38][C:39]=1[CH2:40][OH:41])[CH2:13][O:14][C:15]1[CH:16]=[C:17](/[C:21](/[CH2:35][CH3:36])=[CH:22]/[CH:23]=[CH:24]/[C:25]([C:26]([F:27])([F:28])[F:29])([OH:30])[C:31]([F:33])([F:34])[F:32])[CH:18]=[CH:19][CH:20]=1

Participants

Reactant 2

HCID 2724141Tetrabutylammonium Fluoride

HCID 87503950HCID 87503950, compound

Product 1

HCID 59263692HCID 59263692, compound

Procedure

In a manner analogous to example 2m, by reaction of 640 mg (0.89 mmol) of (3E,5E)-6-{3-[3,4-bis(tert-butyldimethylsilanyloxymethyl)benzyloxy]-phenyl}1,1,1-trifluoro-2-trifluoromethylocta-3,5-dien-2-ol with 2.1 ml (2.1 mmol) of a 1.0 M solution of tetrabutylammonium fluoride. A colorless oil is obtained (m=260 mg; Y=60%).

Workup

customA colorless oil is obtained (m=260 mg; Y=60%)

Sources & evidence

ORD record: ord-63ef3f4334f54eb593968eace1918bbd
Source dataset: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07700657B2

Reaction notes

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