Hexafluoroacetone → HCID 87504064, compound

Participants

Reaction Steps

In a manner analogous to example 21, by reaction of 5 g (9.1 mmol) of (E)-1-(3-{2-[3,4-bis(tert-butyldimethylsilanyloxymethyl)-phenyl]ethyl}phenyl)-1-ethyl-but-1-en-3-yne with 4 ml (10 mmol) of a 2.5 M solution of butyllithium and a flow of hexafluoroacetone. The desired product is obtained in the form of a yellow oil (m=3.7 g; Y=57%).

Provenance & Evidence