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HRID644754

反应详情

EQUATION

反应方程式

HRID 644754 的结构方程式

REACTANTS

反应物

3
结构：[BH4-].[Na+]
HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：CNc1ccc(CN2CCN(C(=O)OC(C)(C)C)[C@@H](C)C2)cc1
HCID59262131

未命名化合物

结构：C[C@H]1CN(Cc2ccc(N)cc2Cl)CCN1C(=O)OC(C)(C)C
HCID59262132

未命名化合物

PRODUCTS

生成物

1
结构：CNc1ccc(CN2CCN(C(=O)OC(C)(C)C)[C@@H](C)C2)c(Cl)c1
HCID59262120

未命名化合物

CONDITIONS

反应条件

温度
50 °C

PROCEDURE

实验过程

The title compound was prepared from 1,1-dimethylethyl (2S)-4-[(4-amino-2-chlorophenyl)methyl]-2-methyl-1-piperazinecarboxylate (D104) using a method similar to that described for D3 in Description 3A although the reaction was heated at 50° C. overnight prior to, and for 24 h after addition of sodium borohydride.(3 eq.). MS (ES): MH+ 354/356.