Chloroform → HCID 68578627, compound

Participants

Reaction Steps

1-Bromohexane (1 equivalent) was dissolved in some toluene in a round bottomed flask flushed with nitrogen. Then, lutidine (1 equivalent) was added and the mixture was heated to reflux. During the reaction, a brown product appeared. The reaction was stopped after 8 hours. Afterwards, the solvent was removed under the reduced pressure. A minimum amount of acetonitrile was added to dissolve the residue and ether was added to precipitate the product. The crude product was washed with ether to afford off-white crystals. The yield of the reaction is 83%. 1H NMR (CDCl3, 200 MHz): δ 0.89 (t, 3H), 1.26 (m), 1.85 (m), 2.64 (s, 3H), 2.93 (s, 3H), 4.81 (t, 2H), 7.75(d, 2H), 9.51 (d, 1H); IR (CHCl3, cm−1): 1398 (C═C), 1635 (C═N), 2975 (N—C).

Provenance & Evidence