Ammonium formate → HCID 58662435, compound

Participants

Reaction Conditions

Reaction Steps

4-Benzyloxycarbonylamino-6-ethyl-1,3-dimethyl-1,4,5,6,-tetrahydro-pyrazolo[3,4-b]pyridine-7-carboxylic acid ethyl ester (0.34 g, 0.85 mmol) obtained in step (iii), methanol (5 mL), and ammonium formate were charged to a flask under a nitrogen atomsphere. To this mixture was added 10% Pd/C (50% wet) (0.1 g), and the resulting slurry was heated at about 40° C. for around 1 hour. The reaction mixture was then cooled to room temperature and filtered through Celite™, and the filtrate was concentrated under vacuum to afford the title compound (0.171 g, 76%).

Provenance & Evidence