Hydrogen Bromide → HCID 67319213, compound

Participants

Reaction Steps

Hydrogen bromide (33% in acetic acid) (0.54 mL) was added to the product from step i) (0.238 g) in acetic acid (0.8 mL) at 0° C. The resulting solution was stirred at room temperature for 2 h then t-butyl methyl ether (3 mL) was added and the mixture stirred for 10 min. A gummy solid formed, which was filtered off and triturated with t-butyl methyl ether (4×3 mL) to form a pale orange solid (0.888 g). The solid was dried at 45° C. for 1 h then recrystallised from hot ethanol (˜3 mL) to afford the title product as a white solid (0.040 g).

Provenance & Evidence