HCID 58872472, compound → HCID 58872483, compound

HRID 645106Notes

Reaction equation

HRID 645106 reaction equation
BrC1C=CC=C2C=1C(C1C(O)=CC3OCOC=3C=1)[C:5](=[O:16])N2CCCCC.[CH3:27][O:28][C:29](=[O:49])[CH2:30][N:31]1[C:39]2[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=2)[CH:33]([C:40]2[CH:45]=[CH:44][C:43]([Cl:46])=[CH:42][C:41]=2[OH:47])[C:32]1=[O:48]>>[CH3:27][O:28][C:29](=[O:49])[CH2:30][N:31]1[C:39]2[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=2)[C:33]([C:40]2[CH:45]=[CH:44][C:43]([Cl:46])=[CH:42][C:41]=2[OH:47])([CH2:5][OH:16])[C:32]1=[O:48]

Participants

3

Reactant 2

HCID 58872472HCID 58872472, compoundHCID 588725004-bromo-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1-pentyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 58872483HCID 58872483, compound

Procedure

Following the procedure as described in PREPARATION 1E, and making non-critical variations to replace 4-bromo-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1-pentyl-1,3-dihydro-2H-indol-2-one with methyl[3-(4-chloro-2-hydroxyphenyl)-2-oxo-2,3-dihydro-1H-indol-1-yl]acetate, the title compound was obtained: MS (ES+) m/z 362.5 (M+1) 364.5 (M+1).

Sources & evidence

ORD record
ord-eec42742addd4de3ae5806299c507b6f
Source dataset
uspto-grants-2010_04
Patent number
US07700641B2

Reaction notes

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