Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 645188Generated: November 2, 2026

ethyl (2'-oxo-6,7-dihydro-5H-spiro[indeno[5,6-b]furan-3,3'-indol]-1'(2'H)-yl)acetate → (2'-oxo-6,7-dihydro-5H-spiro[indeno[5,6-b]furan-3,3'-indol]-1'(2'H)-yl)acetic acid

https://huagongshe.com/reaction/645188

Reaction equation

Participants

RoleNameHCIDCharge
Reactantethyl (2'-oxo-6,7-dihydro-5H-spiro[indeno[5,6-b]furan-3,3'-indol]-1'(2'H)-yl)acetateHCID 59263405—
Reactantethyl(2'-oxospiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-1'(2'H)-yl)acetateHCID 59263415—
Product(2'-oxo-6,7-dihydro-5H-spiro[indeno[5,6-b]furan-3,3'-indol]-1'(2'H)-yl)acetic acidHCID 5926341374%

Reaction Steps

Following the procedure as described in EXAMPLE 2, and making non-critical variations using ethyl(2′-oxo-6,7-dihydro-5H-spiro[indeno[5,6-b]furan-3,3′-indol]-1′(2′H)-yl)acetate to replace ethyl(2′-oxospiro[furo[2,3-f][1,3]benzodioxole-7,3′-indol]-1′(2′H)-yl)acetate, the title compound was obtained in 74% yield; MS (ES−) m/z 354 (M−1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07700641B2
Source datasetuspto-grants-2010_04
ORD IDord-1291a51e24b1480e96a63de0b04d5b9f
Source noteuspto-grants-2010_04