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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 645295Generated: October 30, 2026

1'-(diphenylmethyl)-5-pyridin-3-ylspiro[1-benzofuran-3,3'-indol]-2'(1'H)-one → 5-piperidin-3-ylspiro[1-benzofuran-3,3'-indol]-2'(1'H)-one

https://huagongshe.com/reaction/645295

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1'-(diphenylmethyl)-5-pyridin-3-ylspiro[1-benzofuran-3,3'-indol]-2'(1'H)-oneHCID 59263428—
Reactant(diphenylmethyl)-5'-methylspiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-oneHCID 59263474—
Product5-piperidin-3-ylspiro[1-benzofuran-3,3'-indol]-2'(1'H)-oneHCID 66642723—

Reaction Steps

Following the procedure as described in EXAMPLE 1.28, and making non-critical variations using 1′-(diphenylmethyl)-5-pyridin-3-ylspiro[1-benzofuran-3,3′-indol]-2′(1′H)-one to replace 1′-(diphenylmethyl)-5′-methylspiro[furo[2,3-f][1,3]benzodioxole-7,3′-indol]-2′(1′H)-one, the title compound was obtained that was used in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07700641B2
Source datasetuspto-grants-2010_04
ORD IDord-4ae7c42cdb41463db2ae5e57ccc1c4f8
Source noteuspto-grants-2010_04